
My Perscriptions
Prednisone
| Methotexate
| Imuran
| IVIg
| Remicade
| Zoloft
| Cytoxan |Rituximab|
Prednisone
Prednisone is a steroid used
to treat inflammatory conditions of the body, such as
Polymyositis. Prednisone, suppress the immune system
and It relieves inflammation. When you take it, it’s
like a miracle drug however it isn’t with out
its side effects. I’ve listed just some of them:
Some side effects from Prednisone:
- acne
- anxiety
- depression
- dizziness
- Easy bruising
- headache
- increased hair growth
- insomnia
- irregular or absent menstrual periods
- restlessness
- skin rash
- stomach irritation
- swollen face, lower legs, or ankles
- vision problems (cataracts)
- vomiting
- cold or infection that lasts a long
time
- muscle weakness
Here's
some important information I found out about getting
off of prednisone.
Normally
the adrenal glands release about 7½ mgs of cortisol
into the blood stream, more if you're stressed. Cortisol,
also known as cortisone, is a steroid that your adrenal
gland produces naturally. The brain monitors this amount
and regulates the adrenal function. However it can't
tell the difference between its own natural cortisone
or the prednisone your taking. So when someone has been
taking high doses of steroids over a long period of
time (six years for me) the brain may decrease or stop
producing cortisol altogether. If that happens it called
adrenal suppression. That's why it's so important to
taper off slowly to allow the adrenal gland to recover
and produce cortisol at a normal level again. Everyone
is different so I have to pay close attention to my
body when I get below 7 ½ mgs. If I taper down
too fast before my adrenal gland kicks in, I could have
a flare up. If the production of cortisol is permanently
suppressed as a result of taking prednisone for so many
years, then I'll need to continue to take small doses
of prednisone for life.
Methotrexate
Methotrexate, a disease-modifying
anti-rheumatic drug, is considered the standard treatment
for rheumatoid arthritis. It works as a cytotoxic drug
and as an immunosuppressant. 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from Methotrexate::
- upset stomach
- nausea
- vomiting
- loss of appetite
- diarrhea
- mouth sores
Some long-term side effects
from Methotrexate:
- lung damage ( I was on Methotrexate
when I developed Pulmonary Fibrosis)
- liver damage (Methotrexate may also
cause liver damage, although this is rare. Blood tests
will are done on a regular basis to monitor your liver
and bone marrow for changes.)
Imuran
Imuran is an immunosuppressive
drug used to treat autoimmune disorders such as Polymyositis.
Imuran is less potent and less effective than Cytoxan,
but it also has far fewer side effects - That’s
one reason why I am trying to stay on it. Like Cytoxan,
is well tolerated by most individuals.
Its use can cause the white
blood cell count, platelet count, or red blood cell
count to decrease, and it might increase the risk of
developing lymphoma (a cancer involving the lymph glands,
liver and spleen).
My research strongly suggests
that patients taking Imuran should undergo regular blood
tests to monitor their white blood cell, platelet and
red blood cell count so that adjustments in dosage can
be made if tests indicate a serious change in the blood
count.
IVIg
IVIg (Intravenous immunoglobulin)
is made from blood plasma from donors. IVIg is standard
treatment for MS. The only two side effects that I know
of are headache or flu like symptoms.
I was taking IVIg intravenously
each month. A nurse would come to my house and hook
me up to an IV drip. Each treatment lasted about four
hours a day, for three days. It’s a very expensive
treatment and it was hard for me to get it approved
from my Insurance Company.
IVIg worked great for me
in the beginning. My energy level and muscle strength
improved. I was able to come down on the Prednisone
from 40mgs to 5mgs. It gave me my life back. It worked
for about twelve months but as my body started to get
used to it , it was no longer as effective as it had
been. I would start to feel bad two weeks before my
next treatment. My cough came back and that’s
when the Doctors decided I should try Remicade.
Remicade
Remicade is an anti-TNF drug
used for the treatment of Rheumatoid Arthritis. It’s
given by intravenous injection under medical supervision
and often prescribed in combination with methotrexate
– as was my experience. It can reduce symptoms
such as inflammation, stiffness and joint pain.
My
Experience: I didn’t have any
reaction to my first three Remicade treatments however,
during the fourth treatment I went into anaphylaxis
shock. I now premedicate the night before and the day
of the treatment. The key for my treatment is to regulate
the drip to 8 drops per minute for the first hour of
treatment.
In addition to asking your
doctor for more information regarding this treatment,
I found www.remicade.com to be a good source of information.
Zoloft
Zoloft is a prescription
medication that is used to treat depression, panic disorder,
obsessive-compulsive disorder and posttraumatic stress
disorder in adults. You can learn more about Zoloft
by visiting www.zoloft.com.
My
Experience: Depression is an awful thing
to deal with on top of everything else. In March 2001
I started to get depressed after I found out I had Pulmonary
Fibrosis.
March 2001 through February
2002 was the lowest time in my life. My body hit a wall
and there was nothing I could do about it. I blamed
myself for my illness, and for the first time I realized
I had no control over what was happening to me. I was
scared, lonely and had no one to talk to.
Work was my only saving grace.
I made the decision to start
therapy. I had been to a therapist in the past and had
great success with it, however my original therapist
had retired and moved out of state. My new therapist
didn’t work out since the only thing she seemed
to be interested in was the billing. So I was on my
own.
When I looked in the mirror
I didn’t see myself, but someone else who was
taking over my body. I hated getting my picture taken
(as you can tell it’s not a problem now) I didn’t
realize how upset I really was until I started the IVIg
and went down on the Prednisone and Imuran. It’s
a great feeling to over come depression. I’ve
found for me, the most important thing is a positive
outlook on life, and support from family and friends,
remember it can always be worse. The Zoloft worked,
but it didn’t solve my problems it just made it
a little easier getting through the days.
I am happy to say since April 2002 Chris has been my
angel and my support. I feel I may not have met him
if I didn’t go through this, and he’s worth
it. I appreciate everything he’s done for me and
the support he gives me, he’s a retired-Marine
so I know he’ll never give up on me.
I also have a group of wonderful
friends that really understand what I’m going
through. They have listened to me ramble on and on about
new treatments and new things I’m trying. They’ve
seen me at my best and at the worst and they have been
by my side. They’ve been great!
So, a special thank you from
the bottom of my heart for your love and support, you
guys are the best!
Chris,
Christie W, Kit N, Don F, Sue S, Tom & Cheryl, Pam
F, Ellen R, Michael C., Cindy C, Jane G, Grady C. Jackie
M, Vincent P, Tom M. Bob & Robin, Dominic C, Lewis
& Emily, Anita V. Kay S. Alison M.
Cytoxan
Cytoxan is an immunosuppressive
drug used to inhibit the growth of malignant cells.
It may be used alone but is often administered with
other anticancer medications. As with many immunosuppressive
drugs, taking Cytoxan can result in serious side effects,
but it is well tolerated by most.
Individuals taking Cytoxan
have an increased risk of developing malignancies including
leukemia, bladder cancer, and other tumors. It can also
cause temporary or permanent sterility in both women
and men and bleeding from the bladder (drinking, 3 –
4 liters of fluid a day can help prevent bladder problems.
The extra fluid dilutes the urine and causes the individual
to urinate frequently, minimizing the Cytoxan byproducts
contact with the bladder).
Patients may develop shingles
or hair loss. Like Imuran, the use of Cytoxan may predispose
a patient to develop unusual infections, particularly
when it is used in combination with high doses of steroids.
I feel it’s important
to say again that I am not a medical professional nor
do I have any medical training. This is only some of
the information about Cytoxan that I came across during
my own research and personal experience. There is much
more to learn about this potent drug and in fact, all
of the medicines and treatments listed on this web site.
A good place to start a search for your own information
might be through your doctor.
Rituxan
Rituximab, sold under the trade names Rituxan® and MabThera®, is a chimeric monoclonal antibody used in the treatment of B cell non-Hodgkin's lymphoma, B cell leukemia, and some autoimmune disorders such as Myositis and Lupus.
Rituxan is a powerful immunosuppressant that eliminates mature circulating B-cells for up to nine months. Rituxan is approved for CD20-positive, B-cell, non-Hodgkins lymphoma and for moderately-to severely-active rheumatoid arthritis when there has been inadequate response to other treatments. Rituxan is being studied for other indications, and is prescribed off-label for other serious diseases and conditions such as SLE. The sponsor estimates that approximately 10,000 patients with SLE have been treated with Rituxan. Rituxan is also being tested in Mysoits at the University of Pittsburgh. |